RISE (Research Initiative for Scientific Enhancement)
RISE (Research Initiative for Scientific Enhancement)
UNCP Home Spotlights Lonzie Hedgepeth
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Lonzie Hedgepeth

Student

Student Degree

Bachelor of Science

Student Major

Chemistry and Biology

Student Hometown

Rocky Mount, North Carolina

Career Aspirations and Goals:

My aspirations in life has been to become a pharmacologist emphasizing
molecular biology, genetics, and the effects of drug interactions.

Current Research Activities:

The University of North Carolina at Pembroke (Fall 2016-Present): Currently, I am working on a
project exploring the use of medicinal plants by Southeastern American Indians with Dr. Sandefur, in
the Sandefur lab. The objective of this project is to investigate the cellular mechanisms of the efficacy
of medicinal plants. In doing so, we wish to answer two questions: (1) does the decline in the use of
traditional medicines correlates with declining positive health benefits, and (2) do interactions between
currently used traditional medicines and western therapies contribute to health disparities in American
Indian communities?

Other Research Experiences:
The University of North Carolina at Chapel Hill (Summer 2016-Present): During the summer, I
worked with Patrick McCarter on a project which aimed to investigate Mitogen-Activated Protein
Kinases (MAPKs) in budding yeast (Saccharomyces cerevisiae). The objective was to define the
dynamic interactions between the two branches (Sln1, Sho1) in the HOG pathways that both respond
to hyper-osmotic stress and activate the same stress adaption mechanism through the Hog1 MAPK.